Table 1.

Guilt-by-association methods.

	DEPICT and GADO	GENETICA (ours)
Strategy	Guilt-by-association prediction of gene functions using gene sets	Guilt-by-association prediction of gene functions using gene sets
Transcriptional components	Principal component analysis	Independent component analysis
Barcode	Comparison of eigenvector scalars of member genes and nonmember genes using Welch T test	Average of all mixing matrix weights of member genes
Distance metric	Pearson correlation	Distance correlation
Permutation test	No, parametric p values used	Yes, permutation p values used
Reference	5,13	This study