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R6-deficienct laforin knockout mice have decreased total brain glycogen with corresponding reduction in hippocampal LBs. (a) Total brain glycogen measured as μmol glucose/gram fresh weight (FW). (b) LBs quantified as % of hippocampus stained with PASD. n = 5–8 mice/genotype. (C) Hippocampal micrographs showing representative images from indicated genotypes. Images acquired at 20× magnification. Scale bars, 100 μm
