Table 4.
Rates of agreement to participate if offered a trial by race and ethnicity
| Comparison group | White | Black | Hispanic | Asian |
|---|---|---|---|---|
| All studies | ||||
| No. of studies | 16 | 15 | 8 | 6 |
| Rate, % (95% CI) | 56.0 (47.3 to 64.5) | 60.4 (49.5 to 70.8) | 67.1 (57.4 to 76.2) | 63.6% (39.2 to 85.3) |
| By study setting | ||||
| Treatment, % (95% CI) | 53.4 (44.8 to 61.9) | 57.6 (45.1 to 69.6) | 64.9 (52.9 to 76.1) | 61.7 (34.7 to 85.9) |
| Cancer control, % (95% CI) | 75.9 (52.5 to 93.2) | 70.4 (47.1 to 89.6) | 72.5 (54.4 to 87.8) | 79.8 (7.7 to 100) |
| P | .08 | .33 | .48 | .65 |
| By care setting | ||||
| Academic, % (95% CI) | 56.1 (45.7 to 66.2) | 63.8 (49.9 to 76.8) | 72.1 (62.6 to 80.8) | 86.8 (70.3 to 98.1) |
| Community, % (95% CI) | 55.9 (36.1 to 74.7) | 54.2 (35.2 to 72.7) | 53.8 (38.9 to 68.4) | 37.4 (23.3 to 52.4) |
| P | .98 | .43 | .04 | <.001 |
| Compared to White patientsa | ||||
| All studies | ||||
| No. of studies | — | 13 | 7 | 6 |
| Rate, % (95% CI) | — | 58.4 (46.8 to 69.7) | 66.7 (55.1 to 77.4) | 63.6 (39.2 to 85.3) |
| Rate in White patients, % (95% CI) | — | 55.1 (44.3 to 65.6) | 61.2 (47.8 to 73.8) | 56.9 (43.4 to 70.0) |
| OR (95% CI) | — | 1.01 (0.90 to 1.13) | 1.05 (0.92 to 1.20) | 1.06 (0.84 to 1.34) |
| P | — | .88 | .48 | .62 |
| By study setting | ||||
| Treatment trials only | ||||
| No. of studies | — | 11 | 6 | 5 |
| Rate, % (95% CI) | — | 57.6 (43.2 to 71.5) | 65.4 (51.9 to 77.9) | 61.1 (35.6 to 84.1) |
| Rate in White patients, % (95% CI) | — | 51.5 (40.4 to 62.6) | 59.7 (44.6 to 73.9) | 54.4 (39.6 to 68.7) |
| OR (95% CI) | — | 1.04 (0.91 to 1.19) | 1.05 (0.92 to 1.20) | 1.06 (0.84 to 1.34) |
| P | — | .56 | .48 | .62 |
a
Estimated among studies with data on participation rates for both White patients and minority group of interest. “—” indicates no analysis conducted, because the comparison group is White patients. CI = confidence interval; OR = odds ratio.