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. 2020 Jun 17;113(3):309–317. doi: 10.1093/jnci/djaa087

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© The Author(s) 2020. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Circulating tumor fraction and progression free survival (PFS) in PALOMA-3. A) CONSORT and Venn diagram showing analysis of plasma samples from the PALOMA-3 trial. B) Distribution of detected circulating tumor fraction at baseline (n = 401). C) PFS for the palbociclib plus fulvestrant group (n = 259) split by circulating tumor fraction above or below 10%. D) PFS for the placebo plus fulvestrant group (n = 142) split by circulating tumor fraction above or below 10%. P values are log-rank. CI = confidence interval; CNV = copy number variant.