3.
EGFR突变阳性患者PD-L1表达水平与临床病理特征关系
Relationship between PD-L1 expression level and clinicopathological characteristics in EGFR mutation-positive patients
| Item | PD-L1 expression level | P | ||
| < 1.0% (n=94) | 1.0%-49.0% (n=36) | ≥50.0% (n=11) | ||
| EGFR: epidermal growth factor receptor. | ||||
| Gender | 0.454 | |||
| Male | 43 (71.7%) | 14 (38.9%) | 3 (27.3%) | |
| Female | 51 (54.3%) | 22 (61.1%) | 8 (72.7%) | |
| Age (yr) | 0.095 | |||
| < 65 | 55 (58.5%) | 23 (63.9%) | 3 (27.3%) | |
| ≥65 | 39 (41.5%) | 13 (36.1%) | 8 (72.7%) | |
| Smoking status | 0.959 | |||
| Former | 34 (36.2%) | 14 (38.9%) | 4 (36.4%) | |
| Never | 60 (63.8%) | 22 (61.1%) | 7 (63.6%) | |
| Clinical stage | 0.049 | |||
| vI | 35 (37.2%) | 14 (38.9%) | 1 (9.1%) | |
| Ⅱ | 1 (1.1%) | 0 | 0 | |
| Ⅲ | 9 (9.6%) | 5 (13.9%) | 0 | |
| Ⅳ | 49 (52.1%) | 17 (47.2%) | 10 (90.9%) | |
| Pathological type | 0.022 | |||
| Adenocarcinoma | 92 (97.9%) | 36 (100.0%) | 9 (81.8%) | |
| Squamous carcinoma | 1 (1.1%) | 0 | 1 (9.1%) | |
| Others | 1 (1.1%) | 0 | 1 (9.1%) | |