Table 3.
Changes in the activity levels of Sodium, Potassium – ATPase (Na+/K+ -ATPase) in different brain regions of rats during PTZ-induced epilepsy and on Pre-treatment with different of extracts Bacopa monnieri.
| S.No. | Brain area | SC | PTZ | EE + PTZ | nHE + PTZ | CE + PTZ | EAE + PTZ | nBE + PTZ | AE + PTZ | DZ + PTZ |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CC | 5.424{a} | 4.420[b] | 8.799[c] | 7.134[d] | 5.557[ea] | 5.690[fae] | 8.442[g] | 4.153[hb] | 9.118[ic] |
| ±0.334 | ±0.073 | ±0.214 | ±0.140 | ±0.248 | ±0.112 | ±0.118 | ±0.103 | ±0.070 | ||
| (-18.51) | (62.22) | (31.52) | (2.452) | (4.904) | (55.64) | (-23.43) | (68.10) | |||
| [99.07] | [61.40] | [25.72] | [28.73] | (90.99] | [-6.040] | [106.28] | ||||
| 2 | CB | 5.336[a] | 3.656[b] | 7.052[c] | 6.297[d] | 6.708[e] | 7.316[fc] | 8.327[g] | 4.855[h] | 8.466[ig] |
| ±0.057 | ±0.157 | ±0.062 | ±0.103 | ±0.278 | ±0.016 | ±0.158 | ±0.275 | ±0.088 | ||
| (-13.35) | (32.15) | (18.00) | (25.71) | (37.106) | (56.05) | (-9.014) | (58.65) | |||
| [92.88] | [72.23] | [83.47] | [100.10] | (127.76] | [-21.90] | [131.56] | ||||
| 3 | PM | 7.795[a] | 6.180[b] | 9.298[c] | 9.600[dc] | 8.661[e] | 8.879[fe] | 8.998[gcef] | 6.968[h] | 9.975[id] |
| ±0.348 | ±0.065 | ±0.262 | ±0.205 | ±0.185 | ±0.167 | ±0.327 | ±0.025 | ±0.012 | ||
| (-20.71) | (19.20) | (23.15) | (11.10) | (13.90) | (15.43) | (-10.60) | (27.96) | |||
| [50.45] | [55.33] | [40.14] | [43.67] | (45.59] | [-3.430] | [61.40] | ||||
| 4 | HC | 7.676[a] | 6.176[b] | 9.524[c] | 8.795[d] | 8.998[ed] | 9.298[fce] | 9.759[gc] | 5.614[h] | 9.965[ig] |
| ±0.060 | ±0.059 | ±0.312 | ±0 .172 | ±0.126 | ±0.047 | ±0.218 | ±0.242 | ±0.032 | ||
| (-19.54) | (24.07) | (14.57) | (17.22) | (21.13) | (27.13) | (-26.86) | (29.82) | |||
| [54.20] | [42.40] | [45.69] | [50.55] | (58.01] | [-9.099] | [61.35] |
All the values are Mean, ±SD of six individual observations. Values with same Superscript is significant at P < 0.05. Values with different Superscript are non-significant at P < 0.05. Values in ‘( )’parentheses are % change over saline control and values in ‘[ ]’ are % change over PTZ treatment.