Table 4.
Changes in the activity levels of Magnesium – ATPase (Mg2+ -ATPase) in different brain regions of rats during PTZ-induced epilepsy and on Pre-treatment with different extracts Bacopa monnieri.
| S.No. | Brain area | SC | PTZ | EE + PTZ | nHE + PTZ | CE + PTZ | EAE + PTZ | nBE + PTZ | AE + PTZ | DZ + PTZ |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CC | 8.565[a] | 6.479[b] | 9.659[c] | 7.341[d] | 7.219[ed] | 8.984[fa] | 9.615[gc] | 5.695[h] | 9.702[icg] |
| ±0.130 | ±0.297 | ±0.089 | ±0.192 | ±0.078 | ±0.360 | ±0.265 | ±0.096 | ±0.246 | ||
| (-25.64) | (12.77) | (14.29) | (4.063) | (4.892) | (12.25) | (-33.50) | (13.27) | |||
| [49.08] | [13.30] | [11.42] | [38.66] | [48.40] | [-12.10] | [49.74] | ||||
| 2 | CB | 7.899[a] | 5.944[b] | 9.907[c] | 9.149[dc] | 9.538[ecd] | 8.853[fd] | 9.538[gcde] | 5.492[h] | 9.849[ieg] |
| ±0.127 | ±0.053 | ±0.095 | ±0.130 | ±0.380 | ±0.117 | ±0.259 | ±0.389 | ±0.105 | ||
| (-24.74) | (25.42) | (15.82) | (16.96) | (12.07) | (16.951) | (-30.47) | (24.68) | |||
| [66.67] | [53.91] | [60.46] | [48.94] | [60.47] | [-7.604] | [65.69] | ||||
| 3 | PM | 6.261[a] | 4.585[b] | 7.984[c] | 7.387[d] | 6.624[e] | 6.961[f] | 7.782[gc] | 4.251[h] | 6.261[ia] |
| ±0.200 | ±0.099 | ±0.009 | ±0.169 | ±0.157 | ±0.021 | ±0.047 | ±0.165 | ±0.200 | ||
| (-26.68) | (27.51) | (17.98) | (5.797) | (11.21) | (16.30) | (-32.10) | (24.29) | |||
| [74.13] | [61.11] | [44.47] | [51.82] | [69.72] | [-7.284] | [36.55] | ||||
| 4 | HC | 7.912[a] | 5.864[b] | 8.996[c] | 8.600[d] | 8.881[ecd] | 8.502[fd] | 8.391[gdf] | 5.491[h] | 9.041[ice] |
| ±0.119 | ±0.140 | ±0.267 | ±0.327 | ±0.105 | ±0.118 | ±0.081 | ±0.199 | ±0.011 | ||
| (-25.88) | (13.70) | (8.695) | (12.24) | (7.457) | (6.054) | (-30.59) | (14.26) | |||
| [53.41] | [46.65] | [51.44] | [44.98] | [43.09] | [-6.360] | [54.17] | ||||
All the values are Mean, ±SD of five individual observations. Values with same Superscript is significant at P < 0.05. Values with different Superscript are non-significant at P 0.05. Values in ‘( )’parentheses are % change over saline control and values in ‘[ ]’ are % change over PTZ treatment.