Table 2.

IL-6 levels in experimental animals.

Animal groups	IL6 in plasma (pg/ml)	IL6 in aorta (pg/mg tissue protein)
Normal control	15.56 ± 1.600	40.29 ± 3.930
Disease control	38.01 ± 7.585####	494.55 ± 25.660###
Disease + Simvastatin	13.7 ± 0.845****	68.14 ± 5.400**
Disease + GEF 25 mg/kg	33.195 ± 0.845****	304.93 ± 13.100
Disease + GEF 50 mg/kg	18.35 ± 0.345****	37.67 ± 0.250**
Disease + GEF 100 mg/kg	11.645 ± 0.155****	34.28 ± 2.530**

Each value represent Mean ± S.E.M. ###p < 0.001, ####p < 0.0001 when compared to normal control, *p < 0.05,**p < 0.01, ***p < 0.001, ****p < 0.0001 when compared to disease control, using one way ANOVA followed by Bonferroni’s multiple comparison.