Figure 2.

Putative mechanisms of polyphasic myodegeneration in fast-growing broilers. In a white striping affected breast muscle, multiple cellular processes target satellite cell proliferation, oxidative stress alleviation, and enzymatic reprogramming to repair the damaged muscles. The dysfunction of these mechanisms purportedly causes the myopathic defect in the pectoralis major muscle in broiler chickens. Abbreviations: HIF, hypoxia-inducible factor; ROS, reactive oxygen species; SC, satellite cell; GADPH; glyceraldehyde-3-phosphate dehydrogenase, GK, phosphoglycerate kinase 1; LDH, lactate dehydrogenase; NFIL, nuclear factor interleukin.