Table 4.
Correlation coefficients for ileal morphology and gene expression1.
| SLC15A12 | SLC5A13 | GALNT24 | MUC25 | IFNG6 | HSPB77 | |
|---|---|---|---|---|---|---|
| Villus height (μm) | ||||||
| Pearson | 0.36 | 0.23 | 0.17 | 0.30 | 0.16 | −0.19 |
| P-value8 | <0.01 | 0.03 | 0.10 | <0.01 | 0.14 | 0.07 |
| Crypt depth (μm) | ||||||
| Pearson | 0.07 | 0.04 | −0.11 | 0.02 | 0.17 | 0.26 |
| P-value | 0.48 | 0.69 | 0.29 | 0.83 | 0.09 | 0.01 |
| Villus/crypt9 | ||||||
| Pearson | 0.31 | 0.26 | 0.25 | 0.30 | 0.17 | −0.35 |
| P-value | <0.01 | 0.01 | 0.01 | <0.01 | 0.10 | <0.01 |
| Surface area (mm2) | ||||||
| Pearson | 0.17 | 0.11 | −0.04 | 0.11 | 0.04 | −0.11 |
| P-value | 0.09 | 0.30 | 0.67 | 0.28 | 0.69 | 0.30 |
| IEL10 | ||||||
| Pearson | 0.07 | 0.14 | 0.06 | 0.04 | 0.25 | 0.04 |
| P-value | 0.49 | 0.18 | 0.56 | 0.67 | 0.02 | 0.68 |
1
Pearson correlation coefficient for ileal morphology (in rows) and expression level of differentially expressed genes (in columns).
2
SLC15A1 = Solute carrier family 15 member 1.
3
SLC5A1 = Solute carrier family 5 member 1.
4
GALNT2 = Polypeptide N-acetylgalactosaminyltransferase 2.
5
MUC2 = Mucin 2, oligomeric mucus/gel-forming.
6
IFNG = Interferon gamma.
7
HSPB7 = Heat-shock protein family B member 7.
8
P-value for each Pearson correlation coefficient.
9
Villus/crypt = Ratio of villus height to crypt depth.
10
IEL = Number of intraepithelial lymphocytes per 100 epithelial cells.