. 2020 Dec 11;100(3):100919. doi: 10.1016/j.psj.2020.12.017

Table 6.

Effects of dietary squalene supplementation on the hepatic gene expression level of diquat-challenged broilers.

Items	Treatments			SEM¹	P-value
Items	CON	DQ	DQ + SQ	SEM¹	P-value
Nrf2	1.00^b	1.80^a	1.96^a	0.16	0.015
Keap1	1.00	0.94	0.95	0.07	0.942
HO1	1.00	0.82	0.92	0.06	0.540
NQO1	1.00^a,b	0.90^b	1.62^a	0.13	0.034
GPX1	1.00^b	1.89^a	0.94^b	0.17	0.021
SOD1	1.00	1.10	1.34	0.09	0.344
Bcl-2	1.00	0.98	1.46	0.10	0.066
Bax	1.00^b	1.62^a	0.97^b	0.11	0.015
CASP3	1.00^a,b	1.55^a	0.79^b	0.11	0.010
XIAP	1.00	1.02	1.05	0.06	0.947

^a,bMeans within a row with different superscripts are different at P < 0.05.

Abbreviations: Bax, B-cell lymphoma/leukemia 2-associated X protein; Bcl-2, B-cell lymphoma/leukemia 2; CASP3, caspase 3; CON, nonchallenged broilers fed with a basal diet; DQ, diquat-challenged broilers fed with a basal diet; DQ + SQ, diquat-challenged broilers fed with a basal diet supplemented with 1.0 g/kg of squalene; GPX1, glutathione peroxidase 1; HO1, heme oxygenase 1; Keap1, kelch-like ECH-associated protein 1; NQO1, NAD(P)H quinone dehydrogenase 1; Nrf2, nuclear factor erythroid 2–related factor 2; SOD1, superoxide dismutase 1; XIAP, X-linked inhibitor of apoptosis protein.

n = 6.