Fig. 1.

Genetic variants associated with COVID-19 hospitalization at the OAS locus. Variants marked in red have P values less than 1e-5. In Europeans, they are in LD with the index variant (r² ≥ 0.8), forming a haplotype (black bar) with the genomic coordinates chr12: 113,350,796 to 113,425,679. P values are from the HGI (24), excluding the 23andMe data for which only sparse SNP data are available. The x axis gives hg19 coordinates; genes in the region are indicated below. The three OAS genes are transcribed from left to right. Yellow dots indicate rs10735079 (right, the GenOMICC index SNP) and rs1156361 (left, typed by the Human Origins Array).