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Frequencies across time of two Neandertal haplotypes associated with COVID-19 severity. Frequencies for rs1156361 at the OAS locus on chromosome 12 (A) and rs10490770 at the chromosome 3 locus (B). Error bars indicate SE (Wilson scores). Time periods are indicated in years before present (bp). Ancient data are from a compiled dataset (42), and present-day data are from the 1000 Genomes Project (23).
