Fig. 2.

NNTTR antibodies are specific for misfolded conformations of TTR. Heat-treated M-TTR (50 °C for 120 min) (red) that had been freshly purified (within 24 h) and freshly prepared WT TTR (blue) were titrated using the NNTTR-Dx ELISA. 2504A and 4C1 were used as the capture and detection antibodies, respectively.