Table 2.
Confusion factors and FDG PET/CT scan findings in controls (n = 89) and in SSc patients (n = 36)
| Controls (n = 89) | SSc patients (n = 36) | p value | |
|---|---|---|---|
| Potential confusion factors | |||
| Sex, female, no. (%) | 47 (52.8) | 20 (55.6) | 0.78 |
| Age, years, mean ± SD | 61.7 ± 12.8 | 57.9 ± 13.0 | 0.23 |
| BMI, kg/m2, mean ± SD | 25.9 ± 5.1 | 25.3 ± 5.9 | 0.59 |
| Glycemia, g/L, mean ± SD | 1.0 ± 0.3 | 1.0 ± 0.2 | 0.42 |
| Injection-perfusion duration, minutes, mean ± SD | 73.5 ± 12.3 | 73.5 ± 12.0 | 1.0 |
| 18F-FDG PET/CT scan findings, no. (%) | |||
| Lung | |||
| Abnormal interstitial lung pattern | 1 (1.1) | 15 (41.7) | <.001† |
| hv/SUVmax, mean ± SD | 1.5 ± 0.3 | 2.1 ± 1.0 | <.001† |
| S/SUVmax, mean ± SD | 11.1 ± 2.2 | 14.4 ± 6.4 | 0.005† |
| S/Intensities, median (IQR) | 0.0 (0.0; 0.0) | 2.5 (0.0; 10.0) | <.001† |
| Lymph node | |||
| Mediastinal, abnormal pattern | 0 (0.0) | 9 (25.0) | <.001 |
| Hilar, abnormal pattern | 2 (2.2) | 8 (22.2) | <.001 |
| Osteoarticular, abnormal pattern | 2 (2.2) | 1 (2.8) | NA |
| Muscles, abnormal pattern | 2 (2.2) | 3 (8.3) | NA |
| Skin, abnormal pattern | 2 (2.2) | 2 (5.6) | NA |
| Esophagus, abnormal pattern | 81 (91.0) | 26 (72.2) | 0.007 |
| Calcinosis, abnormal pattern | 0 (0.0) | 0 (0.0) | NA |
BMI body mass index, hv/SUVmax highest value of SUVmax among the 10 pulmonary SUVmax, IQR interquartile range, NA non-applicable, SD standard deviation, S/Intensities sum of the 10 pulmonary intensities, S/SUVmax sum of the 10 pulmonary SUVmax, SSc systemic sclerosis. †p value adjusted on BMI, <.001