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. 2021 Mar 1;16:1709–1724. doi: 10.2147/IJN.S289707

Figure 3.

Figure 3

The stability and cytotoxic effect analysis of Mn-IONPs. (A) The hydrodynamic size of Mn-IONPs in C-DMEM-H for different periods (12 hours, 24 hours, 48 hours and 72 hours) based on dynamic light scattering. (B) Zeta potentials of Mn-IONPs in C-DMEM-H for different periods (12 hours, 24 hours, 48 hours and 72 hours). The control group in A and B is Mn-IONPs suspension in milli-Q water. (C) The relative cell viability of RAW264.7 cells treated with Mn-IONPs for 24 hours. (D) The doubling time of RAW264.7 cells treated with Mn-IONPs suspensions at selected concentrations. *p < 0.05; **p <0.01.