Phylogenetic tree of strain NYI.B1-7.01-21, highlighted in red in a clade with other B.1.1.7 sequences. Other samples from New York belonging to this lineage are shown in blue. A whole-genome nucleotide sequence alignment was performed with sequences retrieved from GISAID (https://www.gisaid.org) using MAFFT v7.450 (8) with the parameters Auto for algorithm, scoring matrix of 200PAM/k=2, gap open penalty of 1.53, and offset value of 0.123. The phylogenetic tree was constructed using 1,000 bootstrap replicates and the model TIM2+F, selected as the best-fit model by the IQ-TREE Web server (9).