Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jan 27;3(1):fcab007. doi: 10.1093/braincomms/fcab007

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) (2021). Published by Oxford University Press on behalf of the Guarantors of Brain.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Clinical course and imaging results of Donors 1 and 2. Clinical course (A) shows moment in time of MRI. General mild atrophy is observed (B, F). Ventricles are slightly dilated and Donor 1 shows periventricular white matter lesions (C), Donor 2 shows an increased signal due to an infarct (G). Slight cerebellar atrophy can be seen in both donors (D, E, H, I). Enlargement of the fourth ventricle, but no FXTAS-characteristic middle cerebral peduncle sign can be seen. T2-fluid-attenuated inversion recovery of Donor 2 does not show increased insular and middle cerebral peduncle signal intensities (J, K), no abnormalities in vasculature (K) and no thinning of the corpus callosum (M). CVA, cerebrovascular accident; PNP, polyneuropathy; VD, vascular dementia; PD, Parkinson’s disease; AD, Alzheimer’s disease; CBD, corticobasal degeneration; FTD, frontotemporal dementia; PSP, progressive supranuclear palsy.