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. 2019 Mar 19;76(7):415–423. doi: 10.1093/ajhp/zxy079

Table 5.

Estimated DGIs and Potential for Therapeutic Adjustment (n = 193)a

Drug % Patients Expected to Experience a DGI
 Ondansetron 1.6
 Capecitabine 0.5
 Simvastatin 2.1
 Escitalopram 0.3
 Allopurinol 0
 Citalopram 0.3
 Tacrolimus 0.8
 Codeine 0.2
 Paroxetine 0.1
 Clopidogrel 0.6
 Phenytoin 0.7
 Total 7.1
Recommendation % Patients Expected to be Eligible for Therapeutic Adjustment
 Strong CPIC recommendation 3.8
 Moderate CPIC recommendation 3.3
 Total 7.1

aDGI = drug-gene interaction, CPIC = Clinical Pharmacogenetics Implementation Consortium.