Fig. 2.

Antibody cross-reactivity between coronaviruses: sera of convalescent COVID-19 patients possess antibodies recognizing MERS-specific peptide of HR2 spike protein domain. a Difference between IgG levels recognizing peptide of HR2 domain in S protein of MERS in convalescent SARS-CoV-2 patients and non-infected healthy donors. b ROC curve for discrimination of “anti-coronaviral” IgG antibodies using indicated MERS peptide as antigen. c IgG reactivity in convalescent plasma of SARS-CoV-2 patients towards HR2 domain in S protein of MERS vs RBD part of S protein of SARS-CoV-2. ****p < 0.0001