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The effect of 25B-NBOMe (0.3, 3 mg/kg) and MDMA (10 mg/kg) on the oxidative damage of DNA in the nuclei from the rat frontal cortex. Data are the mean ± SEM (n = 6 animals per group) and represent tail moment shown as the product of the tail length and the fraction of total DNA in the tail. Typical microscopic images of nuclei from control, 25B-NBOMe- and MDMA-treated rats; *p < 0.01 in comparison to control group (t test). DNA damage is presented in arbitrary units
