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. 2021 Mar 6;14:49. doi: 10.1186/s13041-021-00759-w

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — The enhanced anxiety-like behavior in dysbacteriosis mice. a Representative traces in the elevated plus maze test of different groups. The total crossings (b), time spent in open arms and closed arms (c), and velocity of mice (d) were summarized in different groups. (E) Representative traces in open field test of different groups. f–h The travel distance, central zone travel distance, and central zone time of mice were summarized in different group. n = 6 mice per group (one-way ANOVA for b, d and f–h, two-way ANOVA for c). *p < 0.05; **p < 0.01; ***p < 0.001