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. 2021 Mar 6;21:236. doi: 10.1186/s12885-021-07965-8

Table 3.

T1 – T3 Changes in CIPN Patient-Reported Outcomes Between Study Phases

Outcomes Usual Care Mean (SD) Algorithm Mean (SD) Contrast Between Groupsf
Sensory CIPN Severity
 T1a 8.21 (11.77) 7.48 (9.2)

t = 0.06

p = 0.95

90% CI = − 2.64, 2.83

n = 136

 T2a 12.62 (12.83) 9.47 (8.74)
 T3c 12.68 (12.38) 11.21 (11.45)
Motor CIPN Severity
 T1a 5.38 (8.7) 4.93 (6.42)

t = 0.12

p = 0.90

90% CI = −2.28, 2.64

n = 136

 T2b 7.32 (10.57) 7.89 (8.91)
 T3c 8.98 (11.84) 8.04 (9.33)
Worst CIPN Pain Intensity
 T1d 1.38 (2.17) 1.43 (1.79)

t = 0.18

p = 0.86

90% CI = −0.53, 0.65

n = 134

 T2e 2.01 (2.54) 1.97 (2.3)
 T3c 2.05 (2.34) 1.90 (2.01)

Table 3 describes changes in sensory CIPN severity, motor CIPN severity, and worst CIPN pain intensity severity from T1 to T3 between study phases

aN = 69 Usual Care, N = 71 Algorithm

bN = 69 Usual Care, N = 70 Algorithm

cN = 66 Usual Care, N = 72 Algorithm

dN = 69 Usual Care, N = 69 Algorithm

eN = 68 Usual Care, N = 71 Algorithm

fStatistical test to determine whether the change from T1 to T3 was different between study phases