Table 2.
Comparison of clinicopathological features between the PD and the MD groups
| PD group | MD group | p-value | |
|---|---|---|---|
| n | 409 (%) | 50 (%) | |
| Age (years) | |||
| Mean ± SD (range) | 72.1 ± 8.6 (45–91) | 69.7 ± 10.0 (38–86) | 0.136 |
| Sex | |||
| Male | 313 (76.5%) | 38 (76.0%) | 0.934 |
| Female | 96 (23.5%) | 12 (24.0%) | |
| Main component | |||
| Well differentiated | 331 (80.9) | 17 (34.0) | < 0.01 |
| Moderately differentiated | 67 (16.4) | 30 (60.0) | |
| Papillary | 11 (2.7) | 3 (6.0) | |
| Location | |||
| Upper third | 89 (21.8) | 14 (28.0) | 0.251 |
| Middle third | 139 (34.0) | 18 (36.0) | |
| Lower third | 181 (44.2) | 18 (36.0) | |
| Macroscpic type | |||
| Elevated (I,IIa) | 131 (32.0) | 15 (30.0) | 0.388 |
| Flat (IIb) | 3 (0.7) | 1 (2.0) | |
| Depressed (IIc, III) | 232 (56.7) | 24 (48.0) | |
| Complex (elevated+depressed) | 43 (10.5) | 10 (20.0) | |
| Tumor size (mm) | |||
| Mean ± SD (range) | 20.1 ± 15.1 (1–99) | 37.3 ± 25.8 (4–128) | < 0.01 |
| Depth | |||
| Mucosa | 313 (76.5) | 17 (34.0) | < 0.01 |
| Submucosa, < 500 μm | 48 (11.7) | 11 (22.0) | |
| Submucosa, ≥500 μm | 48 (11.7) | 22 (44.0) | |
| Lymphatic invasion | 21 (5.1) | 14 (28.0) | < 0.01 |
| Vascular invasion | 15 (3.7) | 9 (18.0) | < 0.01 |
| Ulceration | 53 (13.0) | 13 (26.0) | < 0.01 |
| First treatment | |||
| ESD | 369 (90.2) | 27 (54.0) | < 0.01 |
| Gastrectomy | 40 (9.8) | 23 (46.0) | |
| Non-curative resection (for ESD) | 46 (12.5) | 15 (55.6) | < 0.01 |
| LNM | 6 (1.5) | 5 (10.0) | < 0.01 |
Abbreviations: PD pure differentiated-type, MD mixed differentiated-type, SD standard deviation, ESD endoscopic submucosal dissection, LNM lymph node metastasis