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. 2021 Mar 6;18:10. doi: 10.1186/s12987-021-00245-4

Table 2.

Western blot analysis of P-gp protein expression levels in brain capillaries isolated from WT and hAPP mice (Fig. 1a)

Protein Wild Type hAPP hAPP-NCZ hAPP-NCZ/CSA
P-gp 100 ± 13 51 ± 3* 102 ± 7 91 ± 6

Data were obtained from optical density measurements and were normalized to β-actin levels; values are given as %control ± SEM (n = 3)

*Indicates statistical significance determined at the 0.05 level for each endpoint compared to control using Dunnett’s many-to-one t-test