Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Mar 6;22:160. doi: 10.1186/s12864-021-07480-x

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

PMC Copyright notice

Fig. 6 — Multi-omics analysis of the MPBP in H. erinaceus. a Heatmap analysis of expressed mRNA involved in MPBP. The cluster with upregulation in HEB or HEC was marked by purple rectangular. Red represents high expression. Blue represents low expression. b The list of DEGs involved in MPBP. Red represents an obvious upregulation; Blue represents an obvious down-regulation. The DEGs were obtained from the transcriptome and proteomics data, respectively. c The MPBP modified from reference [14]. Purple represents the upregulated genes in HEB or HEC in the purple rectangular of Fig. 6a. d STRING enrichment of the expressed mRNA involved in MPBP. e STRING network analysis of the CDC genes. The CDC genes were obtained by the Venn analysis of the co-enriched DEGs using DAVID and STRING enrichment in HEB_vs_HEA and HEC_vs_HEA in Additional file 15. f Heatmap clustering of the expression value of the CDC genes using qPCR and PRM. Yellow indicates high expression, and blue indicates low expression. *Represents the genes with the statistical support by qPCR (P < 0.05) and PRM (P < 0.05)