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. 2021 Feb 28;2021:1298657. doi: 10.1155/2021/1298657

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Copyright © 2021 Hongcai Wang et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Sketch map of the experimental procedure. The six columns represent different groups as control (normal control group), DM (diabetes group), DM+SGEP (diabetic+sham GEP group), DM+GEP1 (diabetic+GEP1 group), DM+GEP2 (diabetic+GEP2 group), and DM+GEP3 (diabetic+GEP3 group). The whole experimental process maintained for 10 weeks. All rats were adapted to the laboratory conditions for one week (from -4 W to -3 W). All electrodes were implanted by the same surgeon in the serosa of the greater curvature of rats in the DM+SGEP and DM+GEP groups (-3 W). Two weeks later (-1 W), streptozotocin (STZ) was injected to establish diabetic models. Gastric electric pacing (GEP) was carried out in the DM+GEP group 30 min/day for 6 weeks.