Table 2.
Larval development assay results.
| Thiabendazole |
Levamisole |
Ivermectin aglycone |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Time post-replacement | EC50 (μM) | Resistance ratioa | R2 | EC50 (μM) | Resistance ratioa | EC95 (μM) | Resistance ratiob | R2 | EC50 (nM) | Resistance ratioa | EC95 (μM) | Resistance ratiob | R2 |
| UGA-SUSC | 0.03 | – | 0.92 | 0.93 | – | 3.87 | – | 0.96 | 0.90 | – | 2.77 | – | 0.89 |
| Pre-replacement | 12.28 | 491.00 | 0.86 | 0.71 | 0.76 | 5.40 | 1.40 | 0.90 | 49.10 | 54.60 | 645.43 | 233.01 | 0.94 |
| 1.5 months | 0.03 | 1.18 | 1.00 | 0.94 | 1.01 | 2.14 | 0.55 | 0.97 | 2.66 | 2.96 | 6.09 | 2.20 | 0.98 |
| 1.5 years | 54.91 | 2195.52 | 0.78 | 1.89 | 2.02 | 6.57 | 1.70 | 0.96 | 18.44 | 20.50 | 88.45 | 31.93 | 0.99 |
| 2.5 years | 28.61 | 1143.94 | 0.78 | 2.73 | 2.92 | 38.53 | 9.96 | 0.93 | 26.12 | 29.04 | 108.03 | 39.00 | 0.97 |
| 3.5 years | 17.85 | 713.71 | 0.85 | 2.87 | 3.07 | 14.69 | 3.80 | 0.82 | 15.99 | 17.78 | 488.51 | 176.36 | 0.93 |
Resistance ratio was calculated as EC50 of tested isolate divided by EC50 of UGA-SUSC.
Resistance ratio was calculated as EC95 of tested isolate divided by EC95 of UGA-SUSC.