Table 1.
Change in total body weight (g) from baseline to 10-weeks post-gavage.
| Housing/Sex | Replicate | Lean Donor | Obese Donor | P-value | |||
|---|---|---|---|---|---|---|---|
| n | ΔWeight (g) ± SD | n | ΔWeight (g) ± SD | ||||
| Conventional Male | 1 | 4 | 11.4 ± 5.5 | 3 | 18.1 ± 3.3 | <0.01 | |
| 2 | 3 | 10.8 ± 1.9 | 4 | 11.9 ± 1.8 | 0.93 | ||
| 3 | 3 | 12.1 ± 0.4 | 4 | 13.5 ± 1.6 | 0.42 | ||
| Conventional Female | 1 | 5 | 6.5 ± 1.2 | 5 | 10.0 ± 5.5 | <0.01 | |
| 2 | 5 | 6.4 ± 2.1 | 5 | 7.2 ± 1.7 | 0.66 | ||
| 3 | 5 | 7.0 ± 1.5 | 5 | 5.6 ± 1.7 | 0.82 | ||
| SPF Male | 1 | 4 | 11.5 ± 3.8 | 4 | 12.5 ± 2.8 | 0.02 | |
| 2 | 4 | 12.0 ± 2.6 | 4 | 11.5 ± 4.8 | 1.00 | ||
| SPF Female | 1 | 5 | 8.0 ± 1.4 | 5 | 6.9 ± 0.6 | 0.04 | |
| 2 | 5 | 7.5 ± 2.2 | 5 | 7.2 ± 1.5 | 1.00 | ||
ANOVA was performed on data from 4- to 10-weeks post-gavage between experimental and control groups. P-values reflect Tukey’s post-hoc comparison between lean and obese groups.