. 2021 Feb 22;12:598788. doi: 10.3389/fendo.2021.598788

Table 3.

Significant results for two-way analysis of variance.

		Treatment		Main Effect		Interaction Effect
		Veh (mean ± SD)	Mel (mean ± SD)	Genotype	Treatment	Genotype × Treatment
Forelimb suspension reflex test	KO	3.543 ± 0.987	3.558 ± 1.464	F=36.721** P<0.001	F=4.297* P=0.044	F=4.206*, P=0.046
Forelimb suspension reflex test	WT	6.021 ± 2.332	8.568 ± 3.125	F=36.721** P<0.001	F=4.297* P=0.044	F=4.206*, P=0.046
Surface righting reflex text	KO	0.269 ± 0.037	0.266 ± 0.043	F=49.422** P<0.001	F=5.247* P=0.027	F=5.247*, P=0.027
Surface righting reflex text	WT	0.219 ± 0.037	0.171 ± 0.027	F=49.422** P<0.001	F=5.247* P=0.027	F=5.247*, P=0.027
Novel object recognition test	KO	0.205 ± 0.096	0.344 ± 0.217	F=67.604** P<0.001	F=32.52** P<0.001	F=6.204*, P=0.017
Novel object recognition test	WT	0.453 ± 0.138	0.808 ± 0.122	F=67.604** P<0.001	F=32.52** P<0.001	F=6.204*, P=0.017

WT, Wild-type mice with HI injury; KO, knockout mice with HI injury; Mel, melatonin; Veh, vehicle; *P < 0.05; **P < 0.001. [Two-way ANOVA, Bonferroni post hoc test (details are shown in text)].