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. 2021 Feb 22;13:630382. doi: 10.3389/fnagi.2021.630382

Figure 4.

Figure 4

Group-level differences in RMFG-based functional connectivity among the subjects and behavioral significance. (A) The results showed the altered FC brain regions among the groups including BSOG, RITG, and RSMG (GRF-corrected, cluster level p < 0.05, voxel-level p < 0.001). (B) Post hoc analysis of the altered FC regions in all the groups (Bonferroni correction, p < 0.05). Box plots show the 25 percentile, the median, and the 75 percentile, whisker plots are in mean ± SD. *Indicates statistical difference (p < 0.05). (C) Significant correlations between the altered FC and cognitive performance in the SCD, MCI, and AD groups (p < 0.01) after controlling the effects of age, gender, education, and GM volumes as covariates of no interest (p < 0.01). AD, Alzheimer's Disease; MCI, Mild Cognitive Impairment; SCD, Subjective Cognitive Decline; HC, Healthy Control; FC, Function Connectivity; BSOG, Bilateral Superior Occipital Gyrus; RFFG, Right Fusiform Gyrus; RSMG, Right Supramarginal Gyrus; GM, Gray Matter; GRF, Gaussian Random Field.