Skip to main content
. 2021 Feb 22;13:630382. doi: 10.3389/fnagi.2021.630382

Figure 5.

Figure 5

Group-level differences in the LPCUN-based functional connectivity across the subjects and behavioral significance. (A) The results showed the altered FC brain regions among the groups including LDCG, LOLF, RCUN, RSTG, RLING, and RFFG (GRF-corrected, cluster level p < 0.05, voxel-level p < 0.001). (B) Post hoc analysis of the altered FC regions in all the groups (Bonferroni correction, p < 0.05). Box plots show the 25 percentile, the median, and the 75 percentile, whisker plots are in mean ± SD. *Indicates statistical difference (p < 0.05). (C) Significant correlations between the altered FC and neuropsychological tests in the SCD, MCI, and AD groups after controlling the effects of age, gender, education, and GM volumes as covariates of no interest (p < 0.01). AD, Alzheimer's Disease; MCI, Mild Cognitive Impairment; SCD, Subjective Cognitive Decline; HC, Healthy Control; FC, Function Connectivity; LDCG, Left Median Cingulate and Paracingulate Gyri; LOLF, Left Olfactory Cortex; RCUN, Right Cuneus; RSTG, Right Superior Temporal Gyrus; RLING, Right Lingual Gyrus; RFFG, Right Fusiform Gyrus; GM, Gray Matter; GRF, Gaussian Random Field.