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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: J Addict Med. 2021 May-Jun;15(3):191–200. doi: 10.1097/ADM.0000000000000736

Table 4:

Lifespan Differences in Mental and Physical Health Correlates of Tranquilizer Sedative Motive Categories

Age Group Motive
Category
Past-Year Major
Depression
Past-Year Suicidal
Ideation
Past-Year Serious
Psychological
Distress
Past-Year Mental
Health Treatment
Past-Year
Emergency
Department Use
Past-Year
Inpatient
Hospitalization
% OR (95%
CI)
% OR (95%
CI)
% OR (95%
CI)
% OR (95%
CI)
% OR (95%
CI)
% OR (95%
CI)
Adolescents (12-17 years) Non-Misuse 12.9 1.00 (ref.) N/A N/A 23.2 1.00 (ref.) 27.7 1.00 (ref.) 4.8 1.00 (ref.)
Sleep-Relax Only 24.2 2.20 (1.58-3.06)*** 43.2 2.52 (1.89-3.35)*** 51.5 2.75 (2.05-3.68)*** 11.2 2.46 (1.60-3.80)***
Any Recreational 39.6 4.67 (3.67-5.93)***+ 48.1 3.05 (2.49-3.75)*** 43.3 2.00 (1.62-2.47)*** 15.0 3.48 (2.62-4.63)***
Young Adults (18-25 years) Non-Misuse 11.2 1.00 (ref.) 8.7 1.00 (ref.) 21.4 1.00 (ref.) 12.8 1.00 (ref.) 28.7 1.00 (ref.) 6.6 1.00 (ref.)
Sleep-Relax Only 20.6 2.04 (1.66-2.51)*** 18.4 2.34 (1.91-2.87)*** 37.9 2.19 (1.79-2.68)*** 25.1 2.19 (1.79-2.68)*** 38.9 1.57 (1.31-1.87)*** 8.1 1.24 (0.92-1.66)
Any Recreational 27.4 3.04 (2.62-3.53)***+ 27.0 3.89 (3.41-4.44)***+ 48.1 3.24 (2.79-3.77)***+ 32.1 3.24 (2.79-3.77)***+ 40.9 1.75 (1.53-1.99)*** 10.4 1.69 (1.34-2.14)***
Early Middle Adults (26-34 years) Non-Misuse 7.8 1.00 (ref.) 5.0 1.00 (ref.) 14.2 1.00 (ref.) 13.8 1.00 (ref.) 26.5 1.00 (ref.) 8.4 1.00 (ref.)
Sleep-Relax Only 16.6 2.21 (1.72-2.83)*** 12.4 2.57 (1.95-3.39)*** 29.9 2.55 (2.06-3.16)*** 30.2 2.55 (2.06-3.16)*** 32.4 1.32 (1.14-1.54)*** 6.6 0.78 (0.56-1.09)
Any Recreational 33.3 5.58 (4.45-6.99)***+ 23.3 5.33 (4.08-6.97)***+ 51.5 4.65 (3.74-5.78)***+ 43.7 4.65 (3.74-5.78)***+ 37.6 1.63 (1.35-1.96)*** 12.7 1.68 (1.22-2.33)**+
Middle Adults (35-49 years) Non-Misuse 6.8 1.00 (ref.) 3.3 1.00 (ref.) 10.2 1.00 (ref.) 15.5 1.00 (ref.) 23.4 1.00 (ref.) 7.3 1.00 (ref.)
Sleep-Relax Only 19.9 3.00 (2.36-3.80)*** 13.7 3.94 (2.99-5.18)*** 31.0 2.95 (2.37-3.68)*** 37.5 2.95 (2.37-3.68)*** 33.4 1.49 (1.19-1.85)** 10.8 1.39 (1.05-1.85)*
Any Recreational 32.5 6.26 (4.82-8.12)***+ 25.2 8.86 (6.25-12.54)***+ 48.3 6.35 (4.96-8.13)***+ 55.0 6.35 (4.96-8.13)***+ 36.1 1.76 (1.35-2.29)*** 13.1 1.81 (1.26-2.59)**
Older Adults (50 and older) Non-Misuse 4.5 1.00 (ref.) 2.3 1.00 (ref.) 5.8 1.00 (ref.) 13.6 1.00 (ref.) 26.1 1.00 (ref.) 13.1 1.00 (ref.)
Sleep-Relax Only 14.1 3.57 (2.47-5.20)*** 9.2 4.42 (2.90-6.72)*** 17.8 3.53 (2.68-4.64)*** 34.5 3.53 (2.68-4.64)*** 30.4 1.26 (0.95-1.68) 16.2 1.30 (0.87-1.94)
Any Recreational 37.7 11.11 (6.87-17.95)***+ 22.4 10.86 (6.04-19.54)*** 43.9 9.55 (5.68-16.04)***+ 61.2 9.55 (5.68-16.04)***+ 39.2 1.57 (0.95-2.58) 27.1 2.12 (1.26-3.57)**
Age Group by Motive Category Interaction t = 6.52
p < 0.0001
t = 6.84
p < 0.0001
t = 7.71
p < 0.0001
t = 8.09
p < 0.0001
t = −1.26
p = 0.21
t = − 0.65
p = 0.52

Data: 2015-18 National Survey on Drug Use and Health

OR = Odds Ratio; 95% CI = 95% confidence interval of the odds ratio

All models controlled for sex, race/ethnicity, household income and population density of residence.

*

denotes p < 0.05

**

denotes p < 0.01

***

denotes p < 0.001

+

denotes significant difference between Sleep and/or Relax Motives Only and Recreational Motives categories (p < 0.01).