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. 2021 Feb 22;9:617980. doi: 10.3389/fped.2021.617980

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Copyright © 2021 Puoti, Rybak, Kiparissi, Gaynor and Borrelli.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Proposed pathophysiologic mechanisms of gastrointestinal symptoms associated with COVID-19 infection. ENS, enteric nervous system; ACE-2, angiotensin-converting enzyme-2.