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. 2021 Feb 22;11:623952. doi: 10.3389/fonc.2021.623952

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Copyright © 2021 Récher

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The design of ongoing prospective trials to evaluate dexamethasone in acute myeloid leukemia (AML). DEXAML-01: patients (18–60 years) with favorable (fav) or intermediate (int) risk in first complete response after induction chemotherapy. DEXAML-02: patients > 60 with favorable or intermediate risk in first line treatment. DEXAML-03: patients > 18 years with refractory or relapsed AML. CR, complete response; R, randomization; HDAC, high dose cytarabine (3 g/m²/12 h on day 1, 3, and 5); DEX, dexamethasone.