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. 2021 Feb 22;11:629560. doi: 10.3389/fonc.2021.629560

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Copyright © 2021 Xu, Zhang, Shen, Yang, Liu, Dai, Sun, Huang and Guo

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The role of YT521-B homology (YTH) domain family proteins in cancer. By combining different downstream targets, YTH domain family proteins promote or inhibit the occurrence and development of cancer. YTHDF1, YTHDF3, and YTHDC2 mainly play a role as cancer promoting factor. YTHDF2 plays diverse roles in different cancers.