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. 2021 Feb 22;12:622394. doi: 10.3389/fpsyt.2021.622394

Table 4.

Characteristics of interventional and control groups (ranged by addictive disorder).

Authors Name of application
Functionalities/specificities
Control group(s)Functionalities
TOBACCO
Baskerville et al. (25) App: Crush the Crave (CTC) version 2.1
Functionalities:
- Information: relapse, craving, medications
- Set quit date and help to choose the quit mode,
- Track money saved, health benefits and number of cig per day
Specificities:
- Positive reinforcement: motivational message, virtual rewards
- Identify cues and help to manage craving (web-based distractions)
On the Road to Quiting (OnRQ)- Self-help guide,
- Informative,
- Similar contents to CTC
BinDhim NF, McGeechan K, Trevena L. (42) App: Quit Advisor Plus
Functionalities:
- Information: quitting options (benefits/risks)
- Quitting agenda
- Quitting benefits tracker
Specificities:
- Decision-aid app to help choose quit method
- Mandatory information
- Customized, systematic and daily motivational messages
Placebo app:
- Non-mandatory information on quit methods
- No structured information on benefits/harms of different quit methods
Bricker et al. (43) App: SmartQuit version 1.0
Functionalities:
- Information on medications
- Motivational messages on reasons to quit
- Customized quit plan (treatments, social support)
- Tips on craving managements
Specificities:
- Craving management based on acceptance and commitment therapy.
- Track number of craving passed without smoking
QuitGuide app:
- Based on US guidelines
- Information on medications
- Motivates to quit
- Personalized quit plan
- Craving management strategies
Crane D, Ubhi HK, Brown J, West R. (45) App: SmokeFree
Functionalities:
- Information on benefits of quitting
- Track progress: number of days without smoking, savings
Specificities:
- Daily missions on craving prevention and management, based on behavioral cognitive therapy.
- Virtual rewards
Placebo app:
- Minimal version
- Excluded missions
Dar R. (46) App: SmokeBeat
Functionalities:
- Monitoring: detected hand to mouth movements predicting smoking, number of cig per day Specificities: (“smart Watch” or connected bracelets)
- Real-time identification of smoking
“Wait list” group:
- No intervention
Garrison et al. (47) App: Craving to quit
Specificities:
- Mindfulness training
- Meditation techniques
- Conscience of craving (RAIN: Recognize, Accept, Investigate and Note)
Placebo app:
- Minimal version
- “Experience sampling/ES”: monitoring of use and real-time craving
Hassandra et al. (48) App: PhoS (Physical activity over smoking)
Functionalities:
- Information on risks of smoking
- Motivational messages to quit
Specificities:
- Craving management by physical exercises
Usual treatment:
- Behavioral cognitive therapy
Krishnan N,Elf JL, Chon S, Golub JE. (49) App: Coach2Quit
Functionalities:
- Measurement of exhaled CO (eCO) twice per day (automatic reminder)
- Information on consumption based on eCO
Usual treatment:
- Brief intervention
Mavrot C,Wittwer S, Etter JF. (50) App: Stop-Tabac
Functionalities:
- Customized tracker: consumption, savings, progress
- Interactive coach: personalized messages on abstinence, craving, high risk situations
- Help to manage craving: messages (SMS) and counseling on relapse prevention, relaxation exercises
- Professional help through quitline/forum
Specificities:
- Customization
- Systematic and automatic messages at degressive frequency (except for relapse)
Placebo app:
- Consumption tracker
- Few impersonalized messages.
O'Connor M, Whelan R, Bricker J, McHugh L. (44) App: SmartQuit version 2.1 (2Morrow)
Functionalities:
- Personalized quit plan
- Determine reasons to quit
Specificities:
- Based on acceptance and commitment therapy (ACT)
- Track craving passed without smoking
- Combined to face to face ACT
Control group 1:
- Face to face ACT Control group 2- Behavioral cognitive therapy
Peiris et al. (51) App: Can't Even Quit
Functionalities:
- Automated motivational messages (frequency established by user) on abstinence and relapse prevention while experiencing craving
- Consumption tracker
Control group:
- No intervention
- Participants encouraged to use smoking cessation support
Tombor et al. (52) App: SmokeFree Baby
Functionalities:
5 modules:
1) Identity: persuasion and modulation of self-image (positive image, accepting his identity as ex-smoker)
2) Stress management: information on tobacco and stress, stress management techniques, relaxation exercises
3) Effects on health: information on harms of smoking and benefits to quit
4) Face to face: social support
5) Behavior: encourage behavior change, alternative solutions to smoking
Placebo app:
- Few tips on cessation
- Non-interactive
ALCOHOL
Bertholet N, Godinho A,Cunningham JA. (53) App: Alcooquizz
Functionalities:
- Information on use and its consequences
- Monitoring of consumption
- Tool to design a driver
Specificities:
- Not automated (app use depends on user)
- Reinforcement of self-efficacy (fix personal objectives)
- Customized normative feedback
- eBAC calculation
Control group:
- No intervention
Crane D, Garnett C, Michie S, West R, Brown J. (54) App: Drink Less
Functionalities:
(5 interventional module)
1) Customized normative feedback
2) Cognitive bias retraining
3) Self-affirmation: identity change
4) Action planning
5) Self-monitoring of consumption and harms
Placebo application:
- Minimal version
- Informative
- Not personalized
Gajecki M, Andersson C, Rosendahl I, Sinadinovic K, Fredriksson M, Berman AH. (57) App: TeleCoach
Functionalities:
- Information on consequences of hazardous drinking
- Monitoring of number of drinks/days
Specificities:
- Relapse prevention skills training:
1) ≪ Say No to Alcohol ≫: analysis of high risks situations, refusal exercise: “say no to alcohol”
2) ≪ Feel better without alcohol ≫: relaxation exercises, positive thinking, urge surfing training
Control group 1:
- Access to app after 6 weeks Control group 2 (58):
- No intervention
Gajecki M,Berman AH, Sinadinovic K, Rosendahl I, Andersson C. (58) App:
1) Promillekoll
2) PartyPlanner
Functionalities:
Promillekoll:
- Real-time monitoring of number of drinks and eBAC calculation
- Specific strategies to maintain eBAC below 0.06% to prevent dangerous drinking
- Information on use and eBAC PartyPlanner
- Simulate and plan use before an event; compared to real consumption afterwards
- Monitoring of number of drinking and eBAC calculation
Control group:
- No intervention
Glass et al. (55) App: A-CHESS
Functionalities:
- Information on addiction
- Motivational messages
- Monitoring of drinks
- Interaction with other drinkers and experts
- Testimony of patients and families
Specificities:
- Identify high risk situations (GPS)
- Craving management by behavioral cognitive therapy
- Customization
- Combined to outpatient addiction treatment
Mutual help:
- Associated to A-CHESS
Gonzalez VM,Dulin PL. (59) App: LBMI-A
Functionalities:
- 7 psycho-educative modules
Specificities:
- Based on real-time assessment and intervention
- Real-time monitoring of craving (intensity, cues)
- Real-time solutions to manage craving
Control group:
- Placebo app: Brief intervention during 1 h on internet on behavior change
- + bibliography: documents on craving management, how to refuse drinking and overcome relapse
Gustafson DH, McTavish FM, Chih M et al. (56) App: A-CHESS
Functionalities:
- Information on addiction
- Motivational messages
- Monitoring of drinks
- Interaction with other drinkers and experts
- Testimony of patients and families
Specificities:
- Identify high risk situations (geolocation)
- Craving management by behavioral cognitive therapy
- Customization
Usual treatment:
- Medications
- Behavioral cognitive therapy
Hides et al. (60) App: Ray's Night Out
Functionalities:
- Information, motivation and technics to maintain consumption goals
- Information about how to reduce risks of intoxication
- Information on physical and behavioral consequences of intoxication
- Monitoring of number of drinks per event
“wait list” group:
- Differed access to app at 1 month
OTHER SUBSTANCES
Liang D, Han H, Du J, Zhao M, Hser YI. (61) App: S-Health
Functionalities:
- Information on risks reduction (text message at predefined time)
- Customized motivational messages on positive/negative affects
Specificities:
- Daily surveys (predefined time/ upon request) on
1) craving intensity,
2) affects,
3) cues (emotions, place, context),
4) responses to stimuli,
5) social context (alone or with a particular person
- Personalization
Placebo app:
- Few informative messages
BINGE EATING DISORDER
Hildebrandt et al. (62) App: Noom monitor
Functionalities:
- Self-monitoring: exercise, meal/snacks, compensatory behaviors, craving, weight
- Personal notes
Specificities:
- Combined use with behavioral cognitive therapy (self-help guide)
Control group:
- Behavioral cognitive therapy only

app, application; cig, cigarettes; eBAC, estimated blood alcohol concentration; US, United States (of America).