Figure 5.

Protein interaction network of shortlisted genes generated by STRING v11. Intermediate regulators are added by STRING. Edges represent protein-protein associations. The type or source of the association can be interpreted using the line colors as follows: cyan, from curated databases (known); magenta, experimentally determined (known); green, gene neighborhood (predicted); red, gene fusions (predicted); dark blue, gene co-occurrence (predicted); green-yellow, text-mining; black, co-expression; purple, protein homology. Colored nodes represent query proteins and the first shell of interactors.