TABLE 2.

Univariate and multivariate analysis of clinicopathological factors associated with the prognostic significance of P4HA1 expression in breast cancer.

Clinical factors	GSE22133
	Univariate			Multivariate
	p-value	HR	CI (95%)	p-value	HR	CI (95%)
P4HA1 expression	0.0097	1.51	1.10–2.07	0.1693	1.34	0.88–2.04
ER status Positive vs. Negative	0.0042	0.62	0.45–0.86	0.8055	0.92	0.51–1.66
PR status Positive vs. Negative	0.0043	0.63	0.46–0.86	0.5944	0.86	0.49–1.48
Grade 1 and 2 vs. 3	0.0531	1.21	0.99–1.48	0.3255	1.12	0.88–1.43
Histological subtypes Basal ERBB2 Luminal A Luminal B Normal-Like	0.2847 0.4776 0.7437 0.4840 0.0880	1.53 1.39 0.88 1.26 3.41	0.70–3.34 0.56–3.45 0.43–1.79 0.65–2.44 0.83–14.00		NA

ER, Estrogen Receptor; PR, Progesterone Receptor; CI, Confidence Interval.