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. 2021 Mar 4;14(5):101058. doi: 10.1016/j.tranon.2021.101058

Fig. 1.

Fig 1

Effect of cytokines on the progression of cervical neoplasia. In general, cytokines have the effects of slowing or preventing the progression of the neoplasm, inducing its progression, or having a dual effect according to the circumstances. Cytokines that prevent progression of the malignancy (┬) include: IL-2, INF-γ, IL-12, IL-21, IL-10, IL-32, IL-37, and TGF-β1; those that induce progression (↑): IL-1, IL-6, IL-8, IL-10, IL-17, IL-32, TGF-β1, MCP-1, and RANTES; and those that may have a dual effect: IL-10, IL-32, and TGF-β1.