Table 1.
Commercial VLP-based vaccines and their characterizations.
| Vaccine Name | Pathogen | Antigen | Expression System | Company | Reference |
|---|---|---|---|---|---|
| Gardasil | HPV1 | L1 protein 6,111,618 | Yeast (S. cerevisiae) | Merck | [164] |
| Cervarix | HPV | L1 protein 1618 | Insect/baculovirus | GSK | [165,166] |
| GenHevac B | HBV | PreS1 + 2 and HBsAg | Mammalian (CHO cells) | Pasteur-Merieux Aventis | [167] |
| Bio-Hep-B | HBV | HBsAg | Mammalian (CHO cells) | BTG (SciGen, FDS Pharma) | [168] |
| DTP-Hep B | HBV | HBsAg | Yeast (P. pastoris) | P.T. Bio Farma | [169] |
| Engerix-B | HBV | HBsAg | Yeast (S. cerevisiae) | GSK | [71,108] |
| Euvax B | HBV | HBsAg | Yeast (S. cerevisiae) | LG Life ScienceS | [170] |
| Gene Vac-B | HBV | HBsAg | Yeast (H. polymorpha) | Serum Inst. of India | [171] |
| Heberbiovac HB | HBV | HBsAg | Yeast (P. pastoris) | CIGB-Heber Biotec | [172] |
| Hepavax-Gene | HBV | HBsAg | Yeast (H. polymorpha) | Crucell | [173] |
| Recombivax HB | HBV | HBsAg | Yeast (S. cerevisiae) | MercK | [174,175] |
| Revac-B | HBV | HBsAg | Yeast (P. pastoris) | Bharat Biotech | [176] |
| Shanvac-B | HBsAg | Yeast (P. pastoris) | Shantha | [177] | |
| Epaxal | HAV | Inactivated HAV RG-SB | Cell-free | Crucell | [22] |
| Inflexal V | Influenza | A (H1N1), A (H3N2), B, HA, NA | Cell-free | Crucell | [21] |
| Hecolin | HEV | capsid protein | Escherichia coli (Chinese market) | Xiamen Innovax Biotech Co | [178] |
1
Pathogen abbreviations.