Table 1.

Risks and protective measures in DI and hyponatremia in times of COVID-19.

	Risks	Protective measures
Diabetes insipidus	Dilutational hyponatraemia as side effect of desmopressin therapy	Delay desmopressin dose once or twice weekly; Advise to regularly control body weight
		Drink to thirst
	High risk for dysnatraemia if admitted to the hospital due to missed desmopressin dose, reduced fluid intake, increased insensible losses and the potential need for diuretic therapy	Endocrine consultation for every patient with DI to reduce prescribing errors and to advise with fluid management
		Patient empowerment
		Appropriate stress dosing of corticosteroids in patients with additional ACTH deficiency
Hyponatraemia	New diagnosis of SIAD after neurosurgical interventions, brain injury or subarachnoid hemorrhage	Advise to limit fluid intake for two weeks following surgery / injury
		Measure body weight daily and aim to stay at eunatraemic weight
		Drink only to thirst
		Know the early symptoms of hyponatraemia