Table 2.

Adjusted mean annual change in 3MS scores^a ß coefficient (SE) with and without incident AF

	Mean annual change no-AF	Mean annual change incident AF	Incident AF vs. no-AF	P value
Model 1	0.101 (0.064, 0.138)	0.409 (0.125, 0.694)	0.308 (0.025, 0.592)	0.03
Model 2	0.121 (0.084, 0.159)	0.344 (0.013, 0.676)	0.222 (−0.108, 0.553)	0.19

AF, atrial fibrillation; 3MS, Modified Mini-Mental State Exam.

Model 1: Adjusted for site, age, sex, race/ethnicity, education.

Model 2: Model 1 plus time-updated systolic blood pressure, diabetes, peripheral arterial disease, stroke, alcohol use, antiplatelet agents, anticoagulants, statin, baseline estimated glomerular filtration rate, and proteinuria.

^aHigher score indicates higher cognitive function.