Fig. 3.

Functional connectivity between M1 and cerebellar neurons. A. Top: average waveform of 10 putative complex spikes (red) and simple spikes (black). Bottom: Raster of 10 simple spike trains aligned by complex spike. B-D. Bar charts comparing mean spiking properties (spike width, spike frequency, irregularity index) of identified cerebellar Purkinje cells, putative Purkinje cells and M1 neurons. P values calculated from Tukey-Kramer multiple comparisons tests (NS, *, ** and *** represents P > 0.05, P < 0.05, P < 0.01 and P < 0.001 respectively). E. Example spike-triggered average of cerebellar LFPs using spikes from an M1 neuron. F. Mean (±s.e.m.) magnitude-squared spike-LFP coherence between M1 neurons and cerebellar LFP (black), and the proportion of neuron-LFP pairs with significant coherence at each frequency (red). G. Proportion of all neuron-LFP pairs exhibiting significant coherence as a function of frequency and sleep phase. H-J. Same analysis as F-H, but between cerebellar spikes and M1 LFPs. K. Example cross-correlogram between an M1 and a cerebellar neuron. L. Mean (±s.e.m.) magnitude-squared spike-spike coherence between M1 and erebellar neuron pairs (black), and the proportion of neuron pairs with significant coherence at each frequency (red). M. Proportion of all neuron pairs exhibiting significant spike-spike coherence as a function of frequency and sleep phase.