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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: Drug Discov Today Dis Models. 2019 Dec 20;32(Pt A):5–11. doi: 10.1016/j.ddmod.2019.10.007

Table 1.

Summary of cellular models discussed in this review.

Cellular model Description References
Cell lines SK-N-SH, SH-S5Y5 and B103, neuro2A, PC12 40, 41, 42–48, 79
Primary cells Astrocytes, neurons, mixed cultures glia/neurons, iPSCs 15–37, 39, 54, 55, 56, 66, 67, 68, 73, 74, 76, 77, 80, 81
Organotypic explants Human fetal or rodent brain slices 38, 99–104
Neuronal progenitors Primary human or rodent neural progenitors or commercially available iPSCs 105–111
Blood brain barrier models Primary human or rodent pericytes, bilayer with astrocytes and endothelial cells, human brain microvascular endothelial cells, human immortalized endothelial cell line (hCMEC/D3), human vein endothelial cells (HUVEC) 116–130