Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Sixteen key DNA‐repair genes in DNA damage repair and signaling pathways
| DSR | SSR | Checkpoint | p53 pathway | |||
|---|---|---|---|---|---|---|
| HR | FA | NHEJ | MMR | BER | ||
| RAD51D | FANCC | MER11A | MLH1 | MUTHY | ATM | TP53 |
| PALB2 | RAD51C | NBN | MSH2 | CHEK2 | ||
| BLM | RAD50 | MSH6 | ||||
| PMS2 | ||||||
BER, base excision repair; DSR, double‐strand repair; FA, Fanconi anemia; HR, homologous recombination; MMR, mismatch repair; NHEJ, nonhomologous end joining; SSR, single‐strand repair.
