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. 2021 Mar 8;23:19. doi: 10.1186/s12968-021-00721-8

Table 2.

Univariable analysis of clinical and CMR characteristics for prediction of adverse events (N = 1342)

MACE Cardiovascular Mortality
Hazard ratio
(95% CI)
p value Hazard ratio
(95% CI)
p value
Age 1.02 (1.01–1.03) 0.007 1.05 (1.03–1.07) < 0.001
Male 1.18 (0.80–1.73) 0.400 1.28 (0.74–2.22) 0.374
Body mass index 0.96 (0.93–1.00) 0.123 0.98 (0.93–1.01) 0.382
Hypertension 0.73 (0.55–0.97) 0.031 0.74 (0.50–1.09) 0.127
Diabetes mellitus 0.91 (0.67–1.25) 0.575 1.14 (0.75–1.71) 0.546
Dyslipidemia 0.89 (0.66–1.18) 0.408 0.76 (0.51–1.12) 0.168
Current or previous smoking 1.09 (0.79–1.51) 0.594 0.96 (0.61–1.52) 0.861
Family history of CAD 0.88 (0.64–1.19) 0.401 1.04 (0.69–1.57) 0.846
Prior PCI 0.85 (0.64–1.13) 0.263 0.56 (0.38–0.83) 0.003
Prior CABG 0.88 (0.64–1.19) 0.401 1.04 (0.69–1.57) 0.846
Stroke 0.76 (0.28–2.05) 0.592 0.74 (0.18–2.99) 0.669
Renal Failure 0.42 (0.06–3.00) 0.387 0.00 (0.00– + ∞) 0.993
Peripheral atheroma 0.81 (0.47–1.39) 0.442 1.01 (0.51–2.00) 0.975
Heart failure hospitalization 1.40 (0.62–3.15) 0.422 1.84 (0.68–5.01) 0.231
Presence of myocardial ischemia 2.52 (1.90–3.34)  < 0.001 2.04 (1.38–3.03)  < 0.001
Number of segments of myocardial ischemia 1.47 (1.39–1.56)  < 0.001 1.40 (1.29–1.53)  < 0.001
Presence of LGE 1.66 (1.13–2.42) 0.009 1.87 (1.08–3.24) 0.025
Number of segments of LGE 1.35 (1.26–1.45)  < 0.001 1.38 (1.25–1.53)  < 0.001
LVEF, per 10% 0.84 (0.75–0.94) 0.003 0.88 (0.75–1.03) 0.101
LV end-diastolic volume index, per 10 ml/m2 1.06 (1.02–1.11) 0.006 1.05 (0.98–1.11) 0.150
LV end-systolic volume index, per 10 ml/m2 1.09 (1.03–1.14) 0.001 1.07 (1.00–1.15) 0.052
RV ejection fraction, % 0.92 (0.75–1.15) 0.490 1.05 (0.78–1.48) 0.980

CABG coronary artery bypass grafting, CAD coronary artery disease, CI confidence interval, CMR cardiovascular magnetic resonance, HF heart failure, LGE late gadolinium enhancement, LV left ventricle, LVEF left ventricular ejection fraction, MACE major adverse cardiac events, MI myocardial infarction, PCI percutaneous intervention, RV right ventricle