Table 2.

Univariate and multivariate cox hazards analysis of the training cohort

	Univariate analysis		Multivariate analysis
Characteristic	HR (95% CI)	P	HR (95% CI)	p
Sex
Male/Female	1.577 (1.163–2.138)	0.003	1.655 (1.191–2.300)	0.003
Tumor size(cm)
<3/3–5/≥5	1.274 (1.093–1.484)	0.002
Tumor multiplicity
Single/Multiple	1.514 (1.160–1.976)	0.002
Cirrhosis
Yes/N0	2.265 (1.201–4.271)	0.012
PVTT
Yes/N0	2.052 (1.497–2.811)	<0.001	1.547 (1.162–2.059)	0.003
Ascites
Yes/N0	2.314 (1.779–3.010)	<0.001	1.304 (0.918–1.852)	0.138
HBsAg
Positive/Negative	0.622 (0.459–0.844)	0.002
NLR
<5, ≥5	1.723 (1.246–2.384)	0.001
HGB(g/L)
<120, ≥120	0.447 (0.343–0.581)	<0.001	0.785 (0.568–1.084)	0.142
PLT(*10^9/L)
<100,≥100	0.690 (0.503–0.948)	0.022
CR (μmoI/L)
<111, ≥111	3.486 (2.116–5.745)	<0.001	2.200 (1.254–3.858)	0.006
AST(U/L)
<40, ≥40	1.908 (1.463–2.489)	<0.001
TBIL (μmol/L)
<18.8, ≥18.8	1.602 (1.232–2.084)	<0.001
ALB(g/L)
< 40, ≥40	0.468 (0.342–0.639)	<0.001
LDH(U/L)
<250, ≥250	1.993 (1.389–2.861)	<0.001
GGT (U/L)
<60, ≥60	2.147 (1.647–2.799)	<0.001	1.495 (1.087–2.056)	0.013
PTA(%)
< 70, ≥70	0.574 (0.440–0.748)	<0.001
CA199(u/ml)
<37, ≥37	2.479 (1.738–3.534)	<0.001
CRP (mg/L)
<5, ≥5	2.545 (1.955–3.313)	<0.001	1.823 (1.341–2.478)	<0.001