Table 2.
Clinical outcomes of COVID-19 patients with asthma and without asthma.
| Outcomes | Asthma (n = 562) | No asthma (n = 2686)a |
|---|---|---|
| Hospitalization | ||
| No. of events | 119 (21) | 487 (18) |
| Person days of follow up (Mean, SD) | 58 (34) | 61 (33) |
| Rate of event per 1000 person days (95%CI) | 3.7 (3.0, 4.3) | 3.0 (2.7, 3.3) |
| Matched unadjusted (95%CI)a | 1.15 (0.96, 1.38) | 1.00 (ref) |
| Partially adjusted hazard ratio (95%CI)b | 1.07 (0.88, 1.29) | 1.00 (ref) |
| Fully adjusted hazard ratio (95%CI)c | 0.99 (0.80, 1.22) | 1.00 (ref) |
| Mechanical ventilation | ||
| No. of events | 15 (3) | 107 (4) |
| Person days of follow up (Mean, SD) | 71 (23) | 71 (24) |
| Rate of event per 1000 person days (95%CI) | 0.4 (0.2, 0.6) | 0.6 (0.5, 0.7) |
| Matched unadjusted (95%CI)a | 0.67 (0.39, 1.15) | 1.00 (ref) |
| Partially adjusted hazard ratio (95%CI)b | 0.65 (0.37, 1.15) | 1.00 (ref) |
| Fully adjusted hazard ratio (95%CI)c | 0.69 (0.36, 1.29) | 1.00 (ref) |
| Death | ||
| No. of events | 7 (1) | 69 (3) |
| Person days of follow up (Mean, SD) | 73 (21) | 73 (21) |
| Rate of event per 1000 person days (95%CI) | 0.2 (0.0, 0.3) | 0.3 (0.3, 0.4) |
| Matched unadjusted (95%CI)a | 0.47 (0.22, 1.02) | 1.00 (ref) |
| Partially adjusted hazard ratio (95%CI)b | 0.50 (0.22, 1.13) | 1.00 (ref) |
| Fully adjusted hazard ratio (95%CI)c | 0.30 (0.11, 0.80) | 1.00 (ref) |
COVID-19, coronavirus disease 2019; SD, standard deviation; CI, confidence interval.
Text in boldface indicates statistical significance, p < 0.05.
a
Age, sex, and, date of SARS-CoV-2 diagnosis matched comparators.
b
Matched on age, sex, and date of SARS-CoV-2 test date and adjusted for age, sex, race, ethnicity, payor, and smoking status.
c
Matched on age, sex, and date of SARS-CoV-2 test date and adjusted for age, sex, race, ethnicity, payor, smoking status, body mass index, and Charlson comorbidity index.