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. 2021 Feb 22;12:615834. doi: 10.3389/fgene.2021.615834

Table 1.

We performed univariate Cox regression analysis with 531 autophagy-related genes (ARGs) based on TCGA-STAD transcriptome data, and identified 42 ARGs that were associated with the overall survival (OS) of gastric cancer (GC) patients (p < 0.05).

Var HR CI95·low CI95·high Z score p value
IRGM 2.664 1.403 5.056 2.996 0.002734
KCNQ1 0.862 0.772 0.962 −2.643 0.008216
STOM 1.231 1.03 1.472 2.281 0.022577
GABARAPL1 1.233 1.012 1.501 2.083 0.037278
CDC37 0.655 0.468 0.916 −2.476 0.013289
HCAR1 1.186 1.037 1.355 2.489 0.012795
PDK4 1.118 1.023 1.221 2.469 0.013565
RRAGD 1.204 1.019 1.423 2.18 0.02923
DYNLL1 1.51 1.011 2.254 2.014 0.044054
CD93 1.208 1.023 1.426 2.229 0.025809
CHMP4C 0.848 0.73 0.985 −2.159 0.030871
BOC 1.145 1.024 1.28 2.377 0.017441
PLOD2 1.34 1.122 1.6 3.229 0.001243
C1orf210 0.844 0.72 0.988 −2.103 0.03544
ANXA5 1.515 1.188 1.931 3.355 7.94e-4
SRPX 1.135 1.017 1.267 2.263 0.023648
MAP1LC3C 1.374 1.036 1.821 2.204 0.027526
PHYHIP 1.409 1.134 1.75 3.096 0.001961
PRKG1 1.185 1.012 1.389 2.107 0.035158
SERPINB10 1.722 1.192 2.486 2.898 0.003757
GABARAPL2 1.986 1.294 3.049 3.137 0.001704
MAP3K12 1.322 1.027 1.702 2.169 0.030051
CPA3 1.125 1.013 1.251 2.192 0.028346
ATG4D 0.75 0.577 0.974 −2.155 0.031178
HPR 1.392 1.137 1.705 3.204 0.001354
FGF7 1.154 1.029 1.293 2.454 0.014131
MAP1LC3B 1.458 1.043 2.038 2.209 0.027205
C5 1.207 1.005 1.449 2.017 0.043656
SFRP4 1.08 1.006 1.159 2.111 0.034734
LENG9 0.802 0.657 0.978 −2.18 0.029247
STK32A 1.488 1.113 1.989 2.686 0.007232
PGK2 2.633 1.191 5.823 2.391 0.016795
PPY 1.353 1.026 1.785 2.138 0.032505
BNIP3 1.162 1.01 1.336 2.106 0.035221
BNIP3L 1.299 1.019 1.658 2.108 0.035059
CXCR4 1.242 1.085 1.422 3.15 0.001633
DLC1 1.25 1.058 1.477 2.623 0.008717
GRID2 1.838 1.055 3.2 2.15 0.031562
HSPB8 1.105 1.012 1.206 2.228 0.025911
MBTPS2 1.315 1.002 1.727 1.973 0.048542
NRG2 1.309 1.029 1.664 2.193 0.028323
NRG3 1.381 1.058 1.803 2.371 0.01773